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ZO® Medical

Multi-Therapy Hydroquinone System 

(precription only)

An all-encompassing system formulated to help treat hyperpigmentation, severe texture damage, sun damage and general skin health restoration.

Melamin™ Skin Bleaching & Correcting Crème – Net Wt. 32 g / 1.12 Oz.
Glycogent™ Exfoliationg Accelerator, 10% Concentration – 30 mL / 1 Fl. Oz.
Melamix™ Skin Lightener & Blending Crème – Net Wt. 32 g / 1.12 Oz.
Ossential® Daily Power Defense – 30 mL / 1 Fl. Oz.
Oclipse® Sunscreen + Primer Broad-Spectrum SPF 30 – Net Wt. 15 mL / 0.5 Fl. Oz.



  • Treats moderate to severe hyperpigmentation, especially melasma

  • Treats severely dry, dull, rough and leathery textured skin to help restore a smooth, healthy glow

  • Great to use as pre/post procedure skin conditioning to help maintain results longer

  • Helps improve overall appearance and quality of skin

ZO® Skin Health

Skin Brightening Program for Hyperpigmentation, Non-Hydroquinone

A multi-product, skin therapy system designed for the treatment of hyperpigmentation without the use of hydroquinone and retinol.

Ossential® C-Bright Serum 10% Vitamin C  – 20 mL / 0.67 Fl. Oz.
Ossential® Brightalive Non-Retinol Skin Brightener – 30 mL / 1 Fl. Oz.
Ossential® Daily Power Defense – 30 mL / 1 Fl. Oz.
Oclipse® Sunscreen + Primer SPF 30 – Net Wt. 15 mL / 0.5 Fl. Oz.



  • Ideal for improving the appearance of hyperpigmentation either when hydroquinone treatment is completed or contraindicated, or as maintenance

  • Ideal for non-specific discoloration (freckles, liver spots or uneven tone)

  • For use when skin brightening is desired

  • This program also reduces the appearance of fine lines and wrinkles


Tretinoin Cream, USP (Emollient) 0.05%

(by prescription only)

A derivative of vitamin A, ReFissa’s® new formulation of tretinoin has been proven in a clinical trial to be effective in the reduction of fine lines and tactile roughness of the skin, as well as in the treatment of irregular pigmentation from the sun. ReFissa is the first and only tretinoin that has exactly what you need to treat fine facial wrinkles in patients with normal to dry skin:

  • 0.05% strength, clinically-proven efficacy

  • Moisturizing emollient base that helps to minimize the redness and over-drying often caused by acne retinoids

  • Fragrance-free formulation to further reduce the potential for allergic or additional irritation that can be caused by added perfumes

Learn more about ReFissa® by clicking here.

Skin Better Science ®

Regenerating AlphaRet® 

Overnight Face Cream

AlphaRet® Overnight Cream FACE goes to work while the skin is at rest, to visibly reduce the appearance of lines, wrinkles and uneven skin tone.

This formula is supercharged with AlphaRet, our new and unique combination of two gold standard ingredients, an alpha hydroxy acid (AHA) and a retinoid. Our revolutionary and proprietary retinoid technology provides visible skin rejuvenation with real retinoid efficacy with little to no irritation. Glycolic acid helps retexturize to increase the efficacy of AlphaRet. Our deeply hydrating formula also contains a powerhouse of peptides and antioxidants to help protect against free radicals. A trilogy of skin soothing ingredients helps keep skin balanced. With consistent nightly use, skin improvement is visible in as little as four weeks.*

Available in two concentrations, AlphaRet Overnight Cream and AlphaRet Intensive Overnight Cream, which contains a higher level of ingredients for increased skin re-texturization.


  • A significant reduction in the appearance of depth and size of wrinkles in as little as four weeks,* with little to no irritation.

  • Proprietary and revolutionary AlphaRet, a new skin rejuvenating technology, is the result of combining two gold standard anti-aging ingredients, a retinoid and alpha hydroxy acid, to create a revolutionary double conjugated retinoid.

  • Glycolic acid helps increase the efficacy of AlphaRet.

  • A targeted peptide blend acts synergistically with AlphaRet resulting in fewer visible age lines.

  • An ultra hydrating blend of squalane niacinamide, ceramides, fatty acids provides deep moisture to help counteract the dryness associated with traditional retinoid based products.

  • A trilogy of skin soothing ingredients including allantoin glycyrrhetinic acid, bisabolol and portulaca extract provides a sensation of calmness.

  • A potent blend of antioxidants helps provide protection against free radicals.

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